If you develop blisters, it’s advised to use Aquaphore or Vaseline. If not, a triple antibiotic like Neosporin or Polysporin will help. In the week following each session, loose fitting clothes are recommend on areas around your tattoo site. You want to avoid something like a belt scraping up against your skin – when will tattoo removal improved.
Drinking lots of water is highly recommended throughout your entire treatment plan. Why? Aside from the huge benefit of ink removal, keeping hydrated helps your skin heal faster. Having dry skin is not ideal before or after any laser treatment. Drinking too much alcohol on a regular basis can suppress your healing results, and increase your risk of developing It may also affect your immune system and dehydrate your skin and body.
The more time you allow your skin to heal, the lower the risk of developing skin related side effects. As a general rule, tattoos furthest from your heart and neck should be spaced out longer. Vascular areas will heal and respond better to treatment. which is the best tattoo removal cream. Itching is fairly common. Once it does start to itch, slap the treatment area rather than scratch it.
Use an SPF of at least 30 on your ink, and the area surrounding. If it gets wet, reapply. Avoid Banana Boat, it should be Zinc based. There you have it! The risk can be as low as 0% with the right technology, skill and aftercare as outlined on this page.
Skin health and immune function are vital to successful, trouble-free, and scar-free tattoo removals. We at City Tattoo Removal DO NOT treat our clients at a level where the tattoo is likely to blister. Blisters for us are an abnormal reaction and we alter a person’s treatment plan should blisters occur (would you recommend tattoo removal).
We recently had a patient start to develop blisters on the treatment site, which is located on her ankle. Our client had previously been treated on multiple occasions with no ill-effects or reported issues during the aftercare period. We changed our client’s treatment plan accordingly, which involved leaving longer periods between treatments and treating at lower levels than previously used.
We took a break from treatment to study what could be causing these issues for her. Our client has had medical investigations undertaken with her GP. She has now been diagnosed with a significant vitamin D deficiency. This got us asking: “What, if anything, does vitamin D have to laser tattoo removal and treatment outcomes?” Well, as it turns out, could be extremely influential to laser tattoo removal aftercare procedures.
It is “fat-soluble prohormone which has endocrine, paracrine and autocrine functions”(1). Traditionally vitamin D is associated with muscle-skeletal health. It helps to keep bones strong and healthy and decreases the risk of muscle weakness (2). It is oftentimes also associated with calcium because one of its primary roles is to control the levels of calcium found in the bloodstream by facilitating its absorption in the body (3).
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Vitamin D deficiencies have been linked with significant health complications such as cardiovascular events, obesity, bone metabolism, metabolic syndrome, type 2 diabetes, various types of cancer, immune disorders, increased mortality, and adverse pregnancy outcomes (5). Modern medicine now acknowledges vitamin D actions and interactions are not confined to the skeletal system.
Simply put, when an individual’s immune system recognizes something in the body which is not its natural DNA, for example, a virus, the immune system mounts an attack against the foreign substance to rid the body of it (6). These immune responses also apply to dead cells or any other foreign body, such as bacteria, even ink particles which make up tattoos.
One of the most important activities recently observed is the role of vitamin D “to enhance and bring to a completion the inflammatory reaction after injury (7).” There is also increasing data linking vitamin insufficiency with common immune disorders. Published clinical observations suggest vitamin D is a key factor linking innate and adaptive immunity, both of which may be compromised in the cause of vitamin D deficiency (8).
Chun et al. noted vitamin D mediated responses that may occur following a pathogen challenge (9) and can influence the body’s innate immune responses to pathogens. Innate immunity can be defined as the rapid activation “following exposure to foreign agents (e.g., bacteria and viruses), and represents a first line of defense, but lacks specificity” (10).
Vitamin D’s importance to immune function is being discovered to the point it is now clear that macrophages (12) and dendritic cells (13) act as messengers between the innate and the adaptive immune systems and are able to respond to the major circulating vitamin D metabolite, thereby “providing a link between the function of these cells and the variations in vitamin D status common to many humans” (14) – how does tattoo removal work.
The effects of vitamin D on the immune system perhaps cannot be understated in the understanding of an increasing body of literature which suggests a link between vitamin D levels, immune disorders, risk of cancer and cancer-associated mortality (15). Vitamin D deficiency has been linked with a multitude of cutaneous disorders including skin disorders, including blistering disorders and infections (16).
What is clear, however is that vitamin D deficiency appears to be a clear marker of ill health, whether it be the cause, or by association. Vitamin D levels have been shown to decrease following thermal injury (18). Al-Terrah et al opined “This may be both as a primary effect of the injury or a secondary response to the injury itself and/or the clinical management initiated such as fluid resuscitation and use of pressure garments” (19).
showed et al. improved muscle recovery and strength in burn patients supplemented with vitamin D and implied that the vitamin D supplementation had positive effects on muscle health and may play a role during rehabilitation. This is the only study thus far investigating the possible therapeutic benefits of vitamin D following a thermal injury.
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sought to investigate the association between vitamin D deficiency and the biomechanics properties of hypertrophic burn scars. The study was conducted over 486 patients and found that vitamin deficiency was significantly related to post burn issues including slow interstitial fluid movements in burns patients (20). Interstitial fluid aids in bringing oxygen and nutrients to cells and to remove waste products from them.
The old fluid drains towards the lymph vessels where it can then be processed and secreted via the body’s waste systems (21). One wonders whether the slowing of interstitial fluid in these cases increases the risk of patients developing blisters after a burn injury. The article did not specifically address this issue.
Khaled Al-Tarrah, at the Institute of Inflammation and Aging in Birmingham, assessed the recovery progress over one year, in patients with severe burns. Professor Lord found “Low vitamin D levels were associated with worse outcomes in burn patients including life-threatening infections, mortality and delayed wound healing.” It was also associated with worse scarring outcomes (22).
The amount of vitamin D reduction did not seem to be related to the severity of the burn, so levels may also be decreased in more minor burn injuries (23). The phenomena of low vitamin D levels following thermal injury was also noted in a study published in 2018 (24).
Vitamin D may have many effects which may be advantageous to burns patients, including immune regulation, promotion and wound healing. Additionally, vitamin D has antibacterial properties which help combat infection and aid in wound healing to burns patients“ (26). Critical to our particular considerations in relation to tattoo removal is this passage from a review article published in 2015: …Dihydroyvitamin D3 regulates the expression of cathelicidin (27) …, an antimicrobial protein that appears to mediate innate immunity in skin by promoting wound healing and tissue repair.
Other studies have shown that cathelicidin modulates inflammation in skin, induces angiogenesis, and improves reepithelialization (the process of restoring the epidermal barrier to reestablish a functional barrier that protects underlying cells from environmental exposure). The active form of vitamin D and its analogs have been shown to up-regulate cathelicidin expression in cultured keratinocytes.
Mouse studies conducted found that when vitamin D was topically applied to the skin before or immediately following irradiation it provided a photo-protective effect with documented effects being decreased DNA damage, reduced apoptosis (the death of cells which occurs as a normal and controlled part of an organism’s growth or development) ,increased cell survival and decreased erythema (superficial reddening of the skin, usually in patches, as a result of injury or irritation causing dilatation of the blood capillaries) (29).
This is much better than data extracted in relation to the United States where it showed more than 90% of dark-skinned and 3/4 of the white-skinned population had a vitamin D deficiency (31). Traditionally, after 2 courses of 4 to 5 weeks, the patient builds up their vitamin D levels – should you pop tattoo removal blisters.
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Dosage levels are checked annually to ensure healthy levels of vitamin D are maintained (33). Randomized control studies conducted by Mir Sadat-Ali et al. showed vitamin D could, in fact, be delivered effectively via the dermal route. Of course, medical supervision is recommended and required for the recommended treatments of vitamin D, however it may, in fact, be very beneficial to apply vitamin D cream after laser treatment to assist vitamin D depletion which may occur after a laser tattoo removal treatment (34).
The observed phenomenon of slowed interstitial fluid in vitamin D deficient individuals could go a long way to explaining the occurrence of blisters after a laser tattoo removal treatment, (conducted within therapeutic guidelines), especially if the treatment is conducted on the distal limbs, which are located the furthest away from the body’s regional lymph nodes.
Vitamin D could also have a significant role to play in the healing and recovery of a treatment site after a laser tattoo removal treatment, therefore consideration could be given to using topical vitamin D creams before and after laser tattoo removal treatments to assist in the healing of the site after treatment.
“Vitamin D and the skin: Focus on a complex relationship: A review” Wedad Z. Mostafa, Rehab A Hegazy, Journal of Advanced Research (215) 6, 793-804, page 7942. “Vitamin D status and its influence on outcomes following major burn injury and critical illness”, Al-Tarrah et al Burns and Trauma (2018) 6:11, page 23.
Mostafa, Rehab A Hegazy, Journal of Advanced Research (215) 6, 793-804, page 7944. Vitamin D status and its influence on outcomes following major burn injury and critical illness”, Al-Tarrah et al Burns and Trauma (2018) 6:11, page 25. Clinical implications of vitamin D deficiency”, Beata Matyjaszek-Matuzek et al, Prz Menopauzalny2015; 14 (2) 75- 81 page 75 and “Vitamin D status and its influence on outcomes following major burn injury and critical illness”, Al-Tarrah et al Burns and Trauma (2018) 6:11, page16.
“The role of Vitamin D in the Immune System as a Pro-Survival Molecule”, Clinical Therapeutics/ Volume 39, number 5, 2017, p9028. “Vitamin D and immune function: an overview”, Hewson M, Proc Nutr Soc 12 Feb;71(1);50-61, page 509. “Impact of Vitamin D on immune function: lessons learned from genome-wide analysis”, Rene F.
https://www.novusbio.com/research-areas/immunology11. https://www.novusbio.com/research-areas/immunology12. “A type of white blood cell, of the immune system, that engulfs and digests cellular debris, foreign substances, microbes, cancer cells, and anything else that does not have the type of proteins specific to healthy body cells on its surface in a process called phagocytosis,”- https://en.wikipedia.org/wiki/Macrophage13. “Antigen-presenting cells of the mammalian immune system.